CSF neopterin levels in CNS inflammatory diseases.
نویسندگان
چکیده
منابع مشابه
P 96: Role of Thrombin in Inflammatory Central Nervous System (CNS) Diseases
Thrombin is a multifunctional enzyme which has key roles in coagulation cascade and inflammatory events. The pro-inflammatory functions of thrombin occur by different mechanisms including increasing mast cell degranulation, up-regulating the expression of cell adhesion molecules (CAMs) and promoting the secretion of inflammatory chemokines and cytokines. Dysregulated signaling functions of thro...
متن کاملInflammatory Diseases of the CNS I: Encephalitis
Introduction Intracranial infections involving the bones of the skull or spine (osteomyelitis), the extradural compartments, the pachymeninges (dura), subdural space, leptomeninges and subarachnoid space are mainly caused by bacteria and occasionally by fungi and viruses (leptomeningitis). The organisms that infect the CNS itself (the brain and the spinal cord) are mainly viruses and bacteria, ...
متن کاملDisease Type- and Status-Specific Alteration of CSF Metabolome Coordinated with Clinical Parameters in Inflammatory Demyelinating Diseases of CNS
Central nervous system (CNS) inflammatory demyelinating diseases (IDDs) are a group of disorders with different aetiologies, characterized by inflammatory lesions. These disorders include multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and idiopathic transverse myelitis (ITM). Differential diagnosis of the CNS IDDs still remains challenging due to frequent overlap of cl...
متن کاملPPAR Regulation of Inflammatory Signaling in CNS Diseases
Central nervous system (CNS) is an immune privileged site, nevertheless inflammation associates with many CNS diseases. Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear hormone receptors that regulate immune and inflammatory responses. Specific ligands for PPARalpha, gamma, and delta isoforms have proven effective in the animal models of multiple sclerosis (MS), Alzhe...
متن کاملThe role of the complement system in CNS inflammatory diseases.
Complement is an important component of both the innate and adaptive immune response that contributes to host defense in a variety of mechanisms, including inflammation, phagocytosis and cell lysis. Complement proteins are produced by all cell types in the CNS, and the same effector functions that protect the host from pathogens can mediate inflammation and tissue destruction in CNS diseases, l...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Clinical Immunology
سال: 1992
ISSN: 0911-4300,1349-7413
DOI: 10.2177/jsci.15.232